Detectors for Chromatography
by What are detectors in chromatography A chromatography detector is a device used in GC or LC to detect components of the mixture being eluted off the chromatography column. There …
Gas chromatography
Gas chromatography (GC) is an analytical technique used to separate and detect the chemical components of a sample mixture to determine their presence or absence and/or …
Cleaning Validation
What is cleaning Validation Cleaning validation is the methodology used to assure that a cleaning process removes chemical and microbial residues of the active, inactive …
Forced Degradation
The FDA and ICH the requirement of stability testing data to understand how the quality of a drug substance and drug product changes with time …
ELSD Detector
An evaporative light scattering detector (ELSD) is a detector used in conjunction with high-performance liquid chromatography (HPLC), Ultra high-performance liquid chromatography (UHPLC), Purification liquid chromatography such as …
RI Detector
RI detectors monitor the difference in RI between the column eluent containing analyte and a reference stream containing mobile phase only. These detectors are the closest …
PDA Detector
What is PDA detector Photodiode array detectors—variously abbreviated as “PDA detectors” or simply “DADs”—are essentially spectrophotometers that transiently measure the absorbance of light by a liquid …
What is HPLC
High-performance liquid chromatography (HPLC) is an analytical technique to separate, identify, and quantify components in a mixture. It is the single biggest chromatography technique essential to …
Handling of samples between Laboratories
OBJECTIVE To lay down a procedure for handling of samples between QC Laboratory. SCOPE This procedure is applicable for the handling of samples between. RESPONSIBILITIES …
Approval of Contract Testing Laboratory Results
OBJECTIVE To describe the procedure for approval of contract testing laboratories results SCOPE This procedure is applicable to the various tests that are carried out …